Can you shoot abg morphine

First of all, the microbeads contained in the capsule are crushed and put aside. Water is poured into the cooker and heated until the first bubbles appear.

Fairly quickly, the crushed powder is added to the lukewarm water and the solution is stirred. Subsequently, the solution is filtered either through a membrane filter only or through a membrane filter that is positioned on top of a cotton filter, called combined filtration. Prepared in this fashion, the solution is still a little viscous, but it goes through membrane filters; the presence of a cotton filter underneath prevents the filter from clogging and enhances the filtration speed.

Many professionals in the field of harm reduction including the author have been wondering for a long time what would be the best technique for the preparation of this drug. This pushed the fund to write a protocol and to subsequently request Ethypharm to perform the lab work on its product. The lack of a clear regulation places health professionals and their patients in condition of random treatment success.

Morphine as an option of opiate substitution, even for a limited number of patients, deserves to be explored and better supervised for the benefit of all. For filtration, the following filters were used Fig. Filters used. In the field of harm reduction, they are called "wheel filters" Sartorius, Germany. This is the successor of the Sterifilt described by Scott [ 14 ] and Roux et al. It is characterized by a larger filtration area, increased filtration speed and decreased risk of clogging during filtration Apothicom, France.

Other materials used are a hot plate to heat the solutions, standard g white paper and a lighter to crush microbeads and a digital microscope Keyence VHX to visualize the insoluble particles in the filtrate. Two preparation practices are thoroughly explored. As the hot method is used most often, it probably results in a reasonable amount of morphine in the solution. However, this method does not resolve any of the complications related to the injection of insoluble particles because the heat renders the solution incompatible with the use of efficient filters.

This preparation method has thus not been explored. We decided to focus on the methods that may result in reduced harm, namely the cold method and the lukewarm method. A mg morphine sulphate capsule was opened, and the microbeads were put on a carefully folded piece of paper. They were crushed using a lighter while inside the paper. The solution was then either directly taken up through a syringe with a G needle or filtered through one of the four filters.

As filtration by suction through wheel filters is facilitated by wetting the membrane, these filters were rinsed with 0. The paper containing the powder was put aside for later use. Two millilitres of water was poured into the cooker, which was then put onto a hot plate until the first bubbles appeared. The solution was subsequently either taken up through a syringe with a G needle or filtered through one of the four filters.

Prior to filtration, wheel filters were rinsed with 0. Rinsing of wheel filters : It is known that wheel filters have a high void volume and retain part of the solution [ 12 , 14 ]. To examine whether more morphine could be extracted by rinsing, one cold and one lukewarm extraction were performed with an additional rinse using 0. Contact and stirring time : All solutions were stirred for 1 min. Three tests were performed per preparation technique. The following results were collected for each sample: total preparation time, total filtration time, volume retention by the used filter, microscopic particle count digital microscope: Keyence VHX and morphine concentration.

Morphine content refers to the total morphine available in the filtrate, e. To ensure proper particle recognition, dispersions of sole components soluble and insoluble in cold and lukewarm water were evaluated. Starch and talc were easily individually recognisable with no significant difference in size and shape of these compounds between cold and lukewarm suspensions.

To measure the morphine concentration, an ICH validated method using high pressure liquid chromatography with fluorescence detection was used. Overall, filtration time and ease seem acceptable for all filters. Filtration was faster using the lukewarm method; membrane filters were associated with slower filtration than the cotton filter, and wheel filter filtration was slowest overall. Without filtration, a large number of insoluble particles are observed in the morphine sulphate solution, consisting of starch and talc particles.

The latter are mainly present in clusters Fig. The cotton filter eliminates mainly starch particles. Though a large number of particles are eliminated by this filter, talc particles are still present in relatively high numbers after filtration Fig.

Fifty-six percent is recovered without filtration; filtration is thus not necessarily associated to a reduced recovery Table 1. Though the hot method has not been tested, these results show that heating the solution to that point is simply not necessary; all the morphine can be recovered using the lukewarm method.

The final morphine content differs to some extent between filters. With both methods, the wheel filter retains more morphine than the other filters. To examine whether more morphine can be recovered by rinsing wheel filters after filtration, these were rinsed using 0.

Stirring duration is thus an important factor. An enhanced duration might improve extraction in cold water, but will be less acceptable to PWID. This difference is probably due to a difficulty in recovering all the viscous suspension from the cooker after a hot preparation technique e.

As mentioned, the virtually complete extraction by Mclean et al. In our study, a rinse with 0. People who use drugs are resourceful. The reason for their reluctance to use a cold water preparation method has been found, and they were proven right.

This method does yield less morphine. To spread information and to convince others to use a particular preparation technique, lab tests can help. For PWID, it is not easy to try to change a preparation practice for a valuable drug that they cannot miss and do not want to lose, even partially, even once. Evidence-based information on solubility and filtration effectiveness can help people to take just that single step that makes their life easier and their drug less harmful in the long run.

When slow release morphine sulphate capsules are diverted by injection, the use of filters is essential to prevent long term complications due to the injection of insoluble drug fillers such as talc and starch. This practice consists of preheating water, followed by adding beforehand crushed microbeads to the solution, then waiting and stirring for about a minute, followed by filtration through a membrane filter.

The three membrane filters tested were equivalent in number of particle reduction. Additional data and figures that support the findings of this study are available. Restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available.

Costes J-M et al. Les usages de drogues illicites en France depuis Prevalence of opioid analgesic injection among rural opioid analgesic users. Drug Alcohol Depend. I recommend a 5mL 5cc oral syringe, and use the forum search engine to find my guide.

But basically you crush up the pill and boil a certain amount of water with some sea salt in it and drop the pill in. For the ms contins I would use about 7 mls for two pills and get back 6 mls of fluid.

I also had put a benadryl in it to negate the histamine. So for one it would be two cap and for two pills it would be three caps. If you mess up, you can add more water and cook it again. I know neither using a q-tip as a filter is good harm reduction. Neither is dropping benadryl in your shot. It is probably pretty bad for you to be honest. But this method gets you a clear solution that you can inject and that was what I was going for at the time.

The first thing I did was link the OP to your guide. The OP did not really seem to understand or like your methods. If I was to do it, I would stick with the way I know how to which has worked for me in the past.

The boil and drop method seemed to work pretty damn well for me and I always got a clear liquid and a good yield. But I am guessing it is not good for your health at all.

The boil and drop method works for MS-Contin, but once again, I have no clue how good it is for your health. I do not IV drugs pills. Hooman Non-standard issue, also a Jr. Quote from: Thoms on October 05, , PM. All that we see or seem Is but a dream within a dream. Along with the higher amount of particles there is the chance of tiny fibers from the filter coming through. I know I never did but in a perfect world ya know. Oops you said cellulose. Maybe someone else has it?

Quote from: Thoms on October 28, , AM. Pages: 1 Go Up. Guy attempts to use dope and coke as truth serum Help me id this pill! Generic 15mg oxycodone Started by Wildcat Oxycodone. Homeless guy spits some truth about life after being incarcerated for Possession Started by Chip In the Media. Opioids are not sleep aids, and can actually worsen sleep research finds Started by Chip Neuroscience.

It appears that you have not registered with dopetalk. To register, please click here Need help or a chat? SMF 2. SimplePortal 2. Re: not a pill guy 15mg blue morphs - can i iv. Unused, brand-new cellulose cigarette filters? Why not?